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REDUCING GLOBAL PERIOPERATIVE RISK


This resource center is jointly hosted by The American Journal of Medicine,
The American Journal of Cardiology, and the Canadian Journal of Cardiology.

Key Highlights

  • POISE 2 was a blinded factorial randomized controlled trial. A total of 10,010 patients were recruited in 135 centers in 23 countries.
  • Participants were ≥45 years old, having non-cardiac surgery, and at risk of cardiovascular complications.
  • Participants were randomized to ASA versus placebo and clonidine versus placebo.

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