REDUCING GLOBAL PERIOPERATIVE RISK
This resource center is jointly hosted by The American Journal of Medicine,
The American Journal of Cardiology, and the Canadian Journal of Cardiology.
KEY HIGHLIGHTS
- MANAGE trial is an international, multicenter, randomized controlled trial with partial 2x2 factorial design involving 84 centers in 19 countries.
- Participants aged ≥45 who underwent noncardiac surgery and sustained a myocardial infarction after noncardiac surgery (MINS) were included in the trial.
- The study randomized 1754 patients to dabigatran or placebo and 556 patients were randomized to omeprazole or placebo.
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