key Findings
-
Among the first 15,000 patients who had fourth-generation Troponin T (TnT) measured, the peak postoperative TnT measurement during the first 3 days after surgery was significantly associated with 30-day mortality.
-
MINS occurred in 8% of the study population, and 85% of MINS would have been missed without perioperative troponin monitoring.
-
Post-op variables predicting death at 30 days after surgery included MINS [(TnT ≥0.03) Adjusted HR (95% CI) 3.87 (2.96-5.08)], Sepsis [Adjusted HR (95% CI) 7.18 (5.17-9.97)], Stroke [Adjusted HR (95% CI) 3.50 (2.05-5.97)], and PE [Adjusted HR (95% CI) 6.11 (3.18-11.74)].